Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 15/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.57 |
| ▸ | TACR1 | P25103 | 5/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593323 | 0.83 | CYP2D6 (0.57) | SLC6A4SLC6A2TACR1SLC6A3CYP1A2 | |
| Hydrochloric Acid SCHEMBL23532325 | 0.82 | CYP2D6 (0.55) | SLC6A4SLC6A2TACR1SLC6A3CYP1A2 | |
| SCHEMBL2256683 | 0.80 | SLC6A4 (0.56) | SLC6A4SLC6A2TACR1SLC6A3 | |
| SCHEMBL15718470 | 0.79 | SLC6A4 (0.60) | SLC6A4SLC6A2TACR1SLC6A3CYP1A2 | |
| Hydrochloric Acid SCHEMBL3953529 | 0.78 | SLC6A4 (0.54) | SLC6A4SLC6A2TACR1SLC6A3CYP1A2 | |
| SCHEMBL7101455 | 0.76 | CYP2D6 (0.64) | SLC6A4SLC6A2TACR1SLC6A3CYP1A2 | |
| SCHEMBL14593456 | 0.75 | MC4R (0.54) | SLC6A4SLC6A2TACR1SLC6A3CYP1A2 | |
| SCHEMBL5444519 | 0.74 | SLC6A4 (0.76) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL14593425 | 0.74 | CYP3A4 (0.48) | SLC6A4SLC6A2 | |
| SCHEMBL4732656 | 0.74 | SLC6A2 (0.58) | SLC6A4SLC6A2TACR1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |