Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 17/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.58 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049910 | 0.86 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6481202 | 0.82 | TACR1 (0.42) | SLC6A2SLC6A4SLC6A3TACR1 | |
| Hydrochloric Acid SCHEMBL5739425 | 0.81 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4949114 | 0.79 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3975345 | 0.74 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3975368 | 0.74 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3955237 | 0.74 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3972746 | 0.74 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3974156 | 0.74 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14593440 | 0.74 | SLC6A4 (0.57) | SLC6A2SLC6A4SLC6A3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060397-A2 | METHOD OF TREATING THERMOREGULATORY DISFUNCTION | NOVEN THERAPEUTICS, LLC (US) | 2008-05-22 | — | — | WO | disclosed |