Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859582 | 0.82 | CHRM1 (0.46) | TSHRALOX15CHRM1CHRM2CHRM4 | |
| SCHEMBL23779944 | 0.82 | CHRM1 (0.46) | TSHRALOX15CHRM1CHRM2CHRM4 | |
| SCHEMBL9450194 | 0.81 | TSHR (0.42) | TSHRALOX15CHRM1CHRM2CHRM4 | |
| SCHEMBL9346681 | 0.80 | CHRM1 (0.36) | CHRM1SMN1; SMN2TDP1AKR1A1CHRM3 | |
| SCHEMBL28897504 | 0.80 | FOLH1 (0.51) | ALOX15FOLH1 | |
| SCHEMBL28022777 | 0.80 | TSHR (0.42) | TSHRALOX15CHRM1CHRM2CHRM4 | |
| SCHEMBL2481440 | 0.78 | CA2 (0.47) | CHRM1MAPTTDP1AKR1A1CHRM3 | |
| SCHEMBL8694994 | 0.78 | CA2 (0.47) | CHRM1MAPTTDP1AKR1A1CHRM3 | |
| SCHEMBL839295 | 0.78 | TSHR (0.36) | TSHRALOX15CHRM1CHRM2CHRM4 | |
| SCHEMBL839296 | 0.78 | TSHR (0.36) | TSHRALOX15CHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166416-B2 | Protecting groups in polymers, photoresists and processes for microlithography | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-01-23 | — | — | US | disclosed |