Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1458850 | 0.82 | DHODH (0.39) | SCN10AKDM4EAAK1LMNACYP1A2 | |
| SCHEMBL1458509 | 0.81 | KDM1A (0.39) | SCN10AHTR2AHTR2CHTR2BAAK1 | |
| SCHEMBL23040982 | 0.77 | C1R (0.41) | PDE2AC1RKDM4EPARP1APP | |
| SCHEMBL29636633 | 0.77 | C1R (0.41) | PDE2AC1RKDM4EPARP1APP | |
| SCHEMBL2531193 | 0.77 | C1R (0.43) | C1RKDM4EBACE1PARP1APP | |
| SCHEMBL29909108 | 0.77 | C1R (0.43) | C1RKDM4EBACE1PARP1APP | |
| SCHEMBL1459550 | 0.71 | TAAR1 (0.40) | C1RKDM4EBACE1PARP1F7 | |
| SCHEMBL1459549 | 0.70 | PDE2A (0.44) | PDE2AC1RAPPHTTNLRP3 | |
| SCHEMBL28710939 | 0.70 | KDM4E (0.58) | C1RKDM4EAPPLMNA | |
| Ammonia Solution, Strong SCHEMBL3496901 | 0.70 | CTSD (0.40) | C1RKDM4EBACE1PARP1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796180-B2 | Aminoquinazoline compounds for combating invertebrate pests | BASF SE (DE) | 2014-08-05 | — | — | US | disclosed |
| EP-2480537-A1 | AMINOQUINAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-20120178622-A1 | Aminoquinazoline Compounds for Combating Invertebrate Pests | BASF SE (DE) | 2012-07-12 | — | — | US | disclosed |
| WO-2011036074-A1 | AMINOQUINAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2011-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178622-A1 | Aminoquinazoline Compounds for Combating Invertebrate Pests | AAAS, ATL3, H1-3 | SCN10A 3709/4885PDE2A 364/4885HTR2A 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.