SCHEMBL14596157

SCHEMBL14596157

CC=C1N(CC)c2ccc3ccccc3c2C1(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 11/20 0.58
PRMT5 O14744 1/20 0.41
PRMT8 Q9NR22 1/20 0.41
BLM P54132 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
THRB P10828 2/20 0.36
LMNA P02545 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
RECQL P46063 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MLNR O43193 1/20 0.36
NR1I2 O75469 1/20 0.36
PGR P06401 1/20 0.36
ADRB1 P08588 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18103640 1.00 PRMT1 (0.58) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL11301967 0.87 PRMT1 (0.59) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL18101179 0.85 PRMT1 (0.55) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL19114452 0.81 PRMT1 (0.42) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL13762710 0.81 PRMT1 (0.42) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL6955702 0.79 PRMT1 (0.52) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL2846009 0.78 PRMT1 (0.49) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL22848433 0.78 PRMT1 (0.57) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL2846007 0.78 PRMT1 (0.49) PRMT1PRMT5PRMT8BLMMEN1
SCHEMBL13811404 0.76 PRMT1 (0.55) PRMT1PRMT5PRMT8BLMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007034616-A1 TWO-PHOTON-ABSORBING RECORDING MEDIUM, TWO-PHOTON-ABSORBING RECORDING/REPRODUCING METHOD, AND TWO-PHOTON-ABSORBING RECORDING/REPRODUCING APPARATUS FUJIFILM CORPORATION (JP) 2007-03-29 WO disclosed