SCHEMBL6955702

SCHEMBL6955702

C=C1N(CC)c2ccc3ccccc3c2C1(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 8/20 0.52
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
PRMT5 O14744 1/20 0.38
PRMT8 Q9NR22 1/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 4/20 0.38
THRB P10828 2/20 0.38
LMNA P02545 2/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ELANE P08246 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
MAPK1 P28482 2/20 0.36
BLM P54132 1/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 2/20 0.35
APAF1 O14727 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13194376 0.88 PRMT1 (0.45) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL13877782 0.85 PRMT1 (0.42) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL13877789 0.84 PRMT1 (0.42) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL17342567 0.82 PRMT1 (0.40) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL6574797 0.80 MAPT (0.42) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL14596157 0.79 PRMT1 (0.58) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL18103640 0.79 PRMT1 (0.58) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL13171993 0.77 MLNR (0.51) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL18101179 0.76 PRMT1 (0.55) PRMT1MEN1KMT2APRMT5PRMT8
SCHEMBL13382763 0.76 PRMT1 (0.38) PRMT1MEN1KMT2APRMT5PRMT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1152001-B1 SQUARYLIUM COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME KYOWA HAKKO KOGYO KK (JP) 2003-09-03 EP disclosed
US-6596364-B2 Assymetric squarylium dyes for use in digital versatile disc-recording medium KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-07-22 US disclosed
US-20030082330-A1 Squarylium compounds and optical recording medium containing the same KYOWA HAKKO CHEMICAL CO., LTD. (FORMERLY KYOWA YUKA CO., LTD.) (JP) 2003-05-01 US disclosed
EP-1152001-A9 SQUARYLIUM COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME KYOWA HAKKO KOGYO CO., LTD. (JP) 2002-02-27 EP disclosed
EP-1152001-A1 SQUARYLIUM COMPOUND AND OPTICAL RECORDING MEDIUM CONTAINING THE SAME KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-11-07 EP disclosed