Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.38 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylrhodamine SCHEMBL2054818 | 0.84 | MEN1 (0.71) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL18680518 | 0.80 | MEN1 (0.58) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL18713197 | 0.78 | MEN1 (0.62) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL10293759 | 0.77 | P2RY6 (0.64) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL16574888 | 0.77 | MEN1 (0.62) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL14399388 | 0.76 | MEN1 (0.64) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL26213880 | 0.76 | MEN1 (0.71) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL12307301 | 0.75 | MEN1 (0.64) | MEN1THRBRECQLBLMKMT2A | |
| SCHEMBL14399201 | 0.75 | MEN1 (0.67) | MEN1THRBRECQLBLMKMT2A | |
| Tetramethylrhodamine SCHEMBL29838750 | 0.75 | P2RY6 (0.67) | MEN1THRBRECQLBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166715-B2 | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds | APPLERA CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |