Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14596241 | 0.91 | INSR (0.42) | INSRCREBBPKAT2AKAT2BMAPT | |
| SCHEMBL14596240 | 0.90 | MEN1 (0.43) | INSRMAPTKMT2AMEN1HTT | |
| SCHEMBL20176262 | 0.89 | MAPT (0.37) | MAPTKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11949226 | 0.86 | MAPT (0.41) | CREBBPKAT2AKAT2BMAPTKMT2A | |
| SCHEMBL347455 | 0.86 | MAPT (0.41) | CREBBPKAT2AKAT2BMAPTKMT2A | |
| SCHEMBL13646003 | 0.80 | MAPT (0.41) | MAPTKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL14596242 | 0.79 | CREBBP (0.34) | CREBBPKAT2AKAT2BMAPTKMT2A | |
| SCHEMBL20176261 | 0.78 | MEN1 (0.32) | MAPTKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL13205886 | 0.77 | MAPT (0.39) | MAPTKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL347151 | 0.77 | HTT (0.38) | MAPTKMT2AMEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166715-B2 | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds | APPLERA CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166715-B2 | Nitro-substituted non-fluorescent asymmetric cyanine dye compounds | APPLERA CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |