Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.35 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.35 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14597990 | 0.84 | GSK3B (0.43) | STSNAMPTTSHRGABRA1GABRG2 | |
| SCHEMBL12953214 | 0.81 | JAK2 (0.45) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12953174 | 0.80 | TRPC3 (0.52) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10236614 | 0.77 | PDE10A (0.42) | PDE10APOLBSMN1; SMN2 | |
| SCHEMBL12952997 | 0.76 | SIGMAR1 (0.48) | TSHR | |
| SCHEMBL15709940 | 0.73 | TSHR (0.56) | TSHRFKBP1ASLC6A3NPC1RAB9A | |
| SCHEMBL15743128 | 0.73 | TSHR (0.56) | TSHRFKBP1ASLC6A3NPC1RAB9A | |
| SCHEMBL15709938 | 0.73 | TSHR (0.56) | TSHRFKBP1ASLC6A3NPC1RAB9A | |
| SCHEMBL16086901 | 0.71 | PDE10A (0.48) | PDE10APOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12953316 | 0.71 | JAK2 (0.47) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161003-B1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |