Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PROC | P04070 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599621 | 0.98 | SMN1; SMN2 (0.65) | F10SMN1; SMN2CA2F2KMT2A | |
| SCHEMBL5540645 | 0.84 | MAPK1 (0.58) | F10F2ALDH1A1TPSAB1ITGB3 | |
| SCHEMBL14599582 | 0.82 | MAPK1 (0.61) | F10F2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL14599581 | 0.82 | MAPK1 (0.61) | F10F2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL14599527 | 0.82 | MAPK1 (0.61) | F10F2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL14599618 | 0.82 | MAPK1 (0.61) | F10F2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL2344986 | 0.81 | ITGB3 (0.56) | F10CA2F2TPSAB1ITGB3 | |
| SCHEMBL28947192 | 0.81 | F10 (0.54) | F10F2KMT2ATPSAB1ITGB3 | |
| SCHEMBL14132304 | 0.78 | F10 (1.00) | F10SMN1; SMN2F2NPC1HPGD | |
| SCHEMBL25970084 | 0.78 | SMN1; SMN2 (0.96) | SMN1; SMN2ALDH1A1NPC1HPGDPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-01-25 | — | — | US | disclosed |
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021483-A1 | Amidine derivatives for treating amyloidosis | APP, IAPP, GRN | F10 2178/4885SMN1; SMN2 19/4885CA2 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.