Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 4/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600172 | 0.91 | TMEM97 (0.39) | FKBP1ATMEM97ACE | |
| SCHEMBL14600154 | 0.91 | TMEM97 (0.38) | FKBP1ATMEM97PRSS1TMPRSS15ACE | |
| SCHEMBL14600158 | 0.88 | TMEM97 (0.37) | FKBP1ATMEM97ACE | |
| SCHEMBL14600159 | 0.87 | TMEM97 (0.39) | FKBP1ATMEM97ACE | |
| SCHEMBL14600165 | 0.86 | ACE (0.37) | FKBP1ATMEM97ACE | |
| SCHEMBL14600164 | 0.86 | ACE (0.37) | FKBP1ATMEM97ACE | |
| SCHEMBL14600137 | 0.85 | TMEM97 (0.36) | FKBP1ATMEM97ACE | |
| SCHEMBL14600150 | 0.85 | FKBP1A (0.39) | FKBP1ATMEM97ACE | |
| SCHEMBL14600135 | 0.85 | TMEM97 (0.36) | FKBP1ATMEM97ACE | |
| SCHEMBL14600069 | 0.85 | ACE (0.42) | TMEM97PRSS1TMPRSS15ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169805-B2 | Captopril derivatives | NICOX S.A. (FR) | 2007-01-30 | — | — | US | disclosed |