Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600249 | 0.90 | ADORA1 (0.41) | DHODHTP53IGF2BP2ADORA1GFER | |
| SCHEMBL14600467 | 0.86 | DHODH (0.41) | DHODHTP53IGF2BP2ADORA1ADORA3 | |
| SCHEMBL4664691 | 0.85 | ADORA1 (0.43) | DHODHADORA1MEN1KMT2AHTT | |
| SCHEMBL14600207 | 0.84 | TP53 (0.41) | DHODHTP53IGF2BP2ADORA1P2RY1 | |
| SCHEMBL14600223 | 0.83 | ADORA1 (0.43) | DHODHIGF2BP2ADORA1GFERADORA3 | |
| SCHEMBL14600222 | 0.83 | DHODH (0.44) | DHODHTP53IGF2BP2ADORA1LMNA | |
| SCHEMBL14600195 | 0.83 | DHODH (0.42) | DHODHTP53IGF2BP2ADORA1P2RY1 | |
| SCHEMBL14600220 | 0.82 | DHODH (0.46) | DHODHADORA1ADORA3MEN1KMT2A | |
| SCHEMBL14600440 | 0.81 | ADORA1 (0.50) | DHODHTP53IGF2BP2ADORA1ADORA3 | |
| SCHEMBL14600266 | 0.79 | ADORA1 (0.54) | DHODHIGF2BP2ADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |