Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784187 | 0.85 | VEGFA (0.43) | KMT2ASMN1; SMN2HTTTP53KDM4E | |
| SCHEMBL27994026 | 0.85 | VEGFA (0.43) | KMT2ASMN1; SMN2HTTTP53KDM4E | |
| SCHEMBL27478800 | 0.81 | F2 (0.54) | KMT2ASMN1; SMN2HTTTP53KDM4E | |
| SCHEMBL7519636 | 0.77 | KMT2A (0.52) | KMT2AKDM4EHPGDMEN1MAPT | |
| SCHEMBL7521742 | 0.77 | HTT (0.45) | KMT2ASMN1; SMN2HTTTP53KDM4E | |
| SCHEMBL22252623 | 0.77 | TP53 (0.47) | KMT2ASMN1; SMN2HTTTP53KDM4E | |
| SCHEMBL8301883 | 0.77 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2HTTTP53KDM4E | |
| SCHEMBL10072552 | 0.74 | GSK3A (0.34) | ALDH1A1ADORA2BMAPT | |
| SCHEMBL10077158 | 0.73 | KDM4E (0.47) | KMT2ASMN1; SMN2HTTTP53KDM4E | |
| SCHEMBL25045667 | 0.72 | BRD4 (0.36) | SMN1; SMN2ALDH1A1ADORA2BPDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166603-B2 | Dihydropyrimidone inhibitors of calcium channel function | BRISTOL-MYERS SQUIBB CO. (US) | 2007-01-23 | — | — | US | disclosed |