SCHEMBL14600418

SCHEMBL14600418

CC(C)(C)Oc1ccc(-c2c3ccccc3c(-c3ccc4c(c3)C(C)(C)c3cc(-c5c6ccccc6c(-c6c7ccccc7c(-c7ccc(OC(C)(C)C)cc7)c7ccccc67)c6ccccc56)ccc3-4)c3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.38
PDK2 Q15119 3/20 0.35
PPARG P37231 4/20 0.33
PPARA Q07869 3/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PPARD Q03181 1/20 0.33
RIPK1 Q13546 1/20 0.33
ACP1 P24666 1/20 0.31
GPR174 Q9BXC1 1/20 0.31
ALK Q9UM73 1/20 0.30
ACACA Q13085 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14600475 0.99 PDK2 (0.37) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600340 0.99 KIF11 (0.38) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600405 0.97 PDK2 (0.38) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600376 0.96 PDK2 (0.38) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600451 0.96 PDK2 (0.38) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600424 0.95 PDK2 (0.40) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600492 0.95 PDK2 (0.40) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600325 0.95 PDK2 (0.39) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600386 0.95 PDK2 (0.39) KIF11PDK2PPARGPPARACYP2C9
SCHEMBL14600429 0.94 PDK2 (0.41) KIF11PDK2PPARGPPARACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed