Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 15/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600479 | 0.93 | DHODH (0.45) | DHODHMAPTLMNATP53FABP3 | |
| SCHEMBL14600685 | 0.88 | DHODH (0.42) | DHODHFABP3FABP4 | |
| SCHEMBL14600670 | 0.88 | DHODH (0.45) | DHODHTP53FABP3FABP4 | |
| SCHEMBL14600470 | 0.88 | DHODH (0.54) | DHODHMAPT | |
| SCHEMBL14600473 | 0.87 | DHODH (0.59) | DHODH | |
| SCHEMBL14600682 | 0.87 | DHODH (0.55) | DHODH | |
| SCHEMBL14600667 | 0.87 | DHODH (0.38) | DHODHMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL14600726 | 0.86 | DHODH (0.43) | DHODHMAPTLMNATP53FABP3 | |
| SCHEMBL14600725 | 0.85 | MAPT (0.47) | DHODHMAPTFABP3FABP4 | |
| SCHEMBL14600219 | 0.84 | DHODH (0.51) | DHODHMAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |