Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600729 | 0.92 | DHODH (0.47) | DHODHKEAP1NFE2L2 | |
| SCHEMBL14600683 | 0.92 | GFER (0.44) | DHODHKEAP1NFE2L2 | |
| SCHEMBL14600470 | 0.92 | DHODH (0.54) | DHODH | |
| SCHEMBL14600479 | 0.90 | DHODH (0.45) | DHODH | |
| SCHEMBL14600685 | 0.89 | DHODH (0.42) | DHODH | |
| SCHEMBL14600474 | 0.87 | DHODH (0.52) | DHODH | |
| SCHEMBL14600472 | 0.86 | DHODH (0.47) | DHODH | |
| SCHEMBL14600670 | 0.85 | DHODH (0.45) | DHODH | |
| SCHEMBL14600725 | 0.85 | MAPT (0.47) | DHODH | |
| SCHEMBL14600473 | 0.85 | DHODH (0.59) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |