Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 19/20 | 1.00 |
| ▸ | CSNK1D | P48730 | 19/20 | 1.00 |
| ▸ | MAP4K4 | O95819 | 16/20 | 1.00 |
| ▸ | CSNK1A1 | P48729 | 16/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 15/20 | 1.00 |
| ▸ | MAPK8 | P45983 | 13/20 | 1.00 |
| ▸ | PRKD2 | Q9BZL6 | 13/20 | 1.00 |
| ▸ | TAOK1 | Q7L7X3 | 12/20 | 1.00 |
| ▸ | GSK3B | P49841 | 9/20 | 1.00 |
| ▸ | LIMK1 | P53667 | 8/20 | 1.00 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 1.00 |
| ▸ | MINK1 | Q8N4C8 | 13/20 | 0.73 |
| ▸ | MAP4K5 | Q9Y4K4 | 10/20 | 0.73 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.73 |
| ▸ | CSNK1G2 | P78368 | 11/20 | 0.71 |
| ▸ | CSNK1G3 | Q9Y6M4 | 10/20 | 0.71 |
| ▸ | PRKCG | P05129 | 1/20 | 0.71 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.71 |
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | PRKX | P51817 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13342091 | 0.91 | MAPK9 (0.83) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL13342013 | 0.89 | MAPK9 (0.80) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL13342092 | 0.84 | MAPK9 (1.00) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL3523159 | 0.83 | MAPK9 (1.00) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL3663948 | 0.83 | MAPK9 (1.00) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL13368470 | 0.83 | MAPK9 (0.73) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL3724163 | 0.76 | MAPK9 (1.00) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL3525735 | 0.76 | MAPK9 (0.63) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL3525985 | 0.76 | MAPK9 (0.62) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 | |
| SCHEMBL3663739 | 0.73 | MAPK9 (1.00) | MAPK9CSNK1DMAP4K4CSNK1A1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028051-A2 | NOVEL IMIDAZO BASED HETEROCYCLES | ABBOTT LABORATORIES (US) | 2007-03-08 | — | — | WO | disclosed |