Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | DHODH | Q02127 | 14/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14600459 | 0.93 | DHODH (0.49) | ADORA1DHODH | |
| SCHEMBL4667038 | 0.91 | ADORA1 (0.39) | ADORA1DHODHADORA3 | |
| SCHEMBL14600994 | 0.89 | ADORA1 (0.46) | ADORA1DHODHADORA3 | |
| SCHEMBL14600257 | 0.85 | DHODH (0.50) | ADORA1DHODHADORA3 | |
| SCHEMBL4666215 | 0.85 | ADORA1 (0.51) | ADORA1DHODHADORA3 | |
| SCHEMBL14600707 | 0.84 | ADORA1 (0.43) | ADORA1DHODHADORA3 | |
| SCHEMBL14600455 | 0.82 | DHODH (0.47) | ADORA1DHODHADORA3 | |
| SCHEMBL14600253 | 0.81 | DHODH (0.46) | ADORA1DHODH | |
| SCHEMBL4668512 | 0.80 | ADORA1 (0.41) | ADORA1DHODHADORA3 | |
| SCHEMBL14600441 | 0.78 | ADORA1 (0.56) | ADORA1DHODHADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |