Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16342390 | 0.83 | TSHR (0.50) | TSHRACHECYP19A1AKR1C3AKR1C2 | |
| SCHEMBL30659234 | 0.79 | PTPRC (0.46) | NPC1RAB9AACHEAKR1C3AKR1C2 | |
| SCHEMBL26355870 | 0.79 | TSHR (0.49) | TSHRACHECYP19A1AKR1C3AKR1C2 | |
| SCHEMBL6799377 | 0.79 | NPC1 (0.68) | TSHRNPC1RAB9AAKR1C3AKR1C2 | |
| SCHEMBL12717419 | 0.78 | TSHR (0.61) | TSHRNPC1RAB9AACHECYP19A1 | |
| SCHEMBL4486234 | 0.78 | MEN1 (0.50) | NPC1RAB9AAKR1C3AKR1C2MEN1 | |
| SCHEMBL18610494 | 0.77 | PTPRF (0.53) | RAB9AMEN1KMT2ALMNAMAPT | |
| SCHEMBL16342549 | 0.76 | SMN1; SMN2 (0.55) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL18585590 | 0.76 | KMT2A (0.51) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL11691049 | 0.76 | ALDH1A1 (0.51) | NPC1RAB9AACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007032936-A2 | AZAFUSED CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-03-22 | — | — | WO | disclosed |