Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550435 | 0.85 | HAO1 (0.64) | MAPTSMN1; SMN2ALDH1A1HAO1MEN1 | |
| SCHEMBL5585568 | 0.84 | HRH3 (0.61) | HRH3SMN1; SMN2ALDH1A1MRGPRX4MAOB | |
| SCHEMBL3891303 | 0.83 | HAO1 (0.61) | MAPTSMN1; SMN2ALDH1A1HAO1BCL2L1 | |
| SCHEMBL22139428 | 0.81 | HRH3 (0.62) | HRH3MRGPRX4 | |
| SCHEMBL20428558 | 0.80 | HAO1 (0.57) | MAPTSMN1; SMN2ALDH1A1HAO1BCL2L1 | |
| SCHEMBL22291713 | 0.79 | HRH3 (0.61) | HRH3SMN1; SMN2MRGPRX4MEN1NPC1 | |
| SCHEMBL17873432 | 0.77 | GSK3B (0.55) | MAPTALDH1A1HAO1PTPN1 | |
| SCHEMBL24066731 | 0.76 | HRH3 (0.57) | HRH3MRGPRX4PTPN1 | |
| SCHEMBL24066732 | 0.76 | HRH3 (0.57) | HRH3MRGPRX4PTPN1 | |
| SCHEMBL26317343 | 0.76 | HRH3 (0.57) | HRH3MRGPRX4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |