Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5585439 | 0.99 | MAPT (0.52) | MAPTRAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL14601436 | 0.93 | MAPT (0.48) | MAPTRAB9ASMN1; SMN2HTTLMNA | |
| Hydrochloric Acid SCHEMBL5585415 | 0.92 | MAPT (0.47) | MAPTRAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL14601435 | 0.91 | LMNA (0.53) | MAPTRAB9ASMN1; SMN2HTTLMNA | |
| Hydrochloric Acid SCHEMBL5585774 | 0.91 | LMNA (0.52) | MAPTRAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL14601444 | 0.87 | LMNA (0.49) | MAPTRAB9ASMN1; SMN2HTTLMNA | |
| Hydrochloric Acid SCHEMBL5585886 | 0.87 | LMNA (0.49) | MAPTRAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL14601438 | 0.84 | MAPT (0.48) | MAPTRAB9ASMN1; SMN2HTTLMNA | |
| SCHEMBL14601442 | 0.83 | NPC1 (0.49) | MAPTRAB9APHGDHNPC1HPGD | |
| Hydrochloric Acid SCHEMBL5585570 | 0.83 | MAPT (0.48) | MAPTRAB9ASMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |