Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5585728 | 0.99 | NPC1 (0.40) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| Hydrochloric Acid SCHEMBL5585733 | 0.99 | NPC1 (0.40) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| SCHEMBL14601440 | 0.91 | NPC1 (0.41) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| Hydrochloric Acid SCHEMBL5585558 | 0.91 | NPC1 (0.41) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| SCHEMBL14601439 | 0.88 | USP2 (0.45) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| SCHEMBL14601435 | 0.88 | LMNA (0.53) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5585950 | 0.87 | USP2 (0.44) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| Hydrochloric Acid SCHEMBL5585774 | 0.87 | LMNA (0.52) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL14601438 | 0.87 | MAPT (0.48) | NPC1RAB9AALDH1A1MAPTNFKB1 | |
| SCHEMBL14601442 | 0.86 | NPC1 (0.49) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |