SCHEMBL14601701

SCHEMBL14601701

O=C(Nc1ccc(I)cc1F)c1cc(Br)ccc1NS(=O)(=O)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CCR9 P51686 6/20 0.60
SLC10A6 Q3KNW5 2/20 0.51
SLC10A2 Q12908 1/20 0.51
SLC10A1 Q14973 1/20 0.51
KDM1A O60341 1/20 0.47
TP53 P04637 2/20 0.45
MAPT P10636 2/20 0.45
GPR27 Q9NS67 2/20 0.45
METAP2 P50579 2/20 0.44
WDR5 P61964 2/20 0.44
LMNA P02545 1/20 0.43
FFAR4 Q5NUL3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14601699 0.85 CCR9 (0.63) CCR9SLC10A6SLC10A2SLC10A1KDM1A
SCHEMBL5597750 0.83 FFAR4 (0.53) CCR9MAPTFFAR4
SCHEMBL5597820 0.81 CCR9 (0.72) CCR9SLC10A6SLC10A2SLC10A1KDM1A
SCHEMBL3243266 0.80 CCR9 (0.70) CCR9SLC10A6SLC10A2SLC10A1KDM1A
SCHEMBL5597824 0.80 CCR9 (0.70) CCR9SLC10A6SLC10A2SLC10A1KDM1A
SCHEMBL14601703 0.80 CCR9 (0.57) CCR9SLC10A6SLC10A2SLC10A1KDM1A
SCHEMBL14601704 0.79 CCR9 (0.64) CCR9SLC10A6SLC10A2SLC10A1KDM1A
SCHEMBL5598059 0.78 CCR9 (0.62) CCR9SLC10A6SLC10A2SLC10A1KDM1A
SCHEMBL14601700 0.78 CCR9 (0.54) CCR9SLC10A6SLC10A2SLC10A1MAPT
SCHEMBL5598199 0.77 CCR9 (0.58) CCR9SLC10A6SLC10A2SLC10A1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070021509-A1 Phosphate transport inhibitors JOZEFIAK THOMAS H 2007-01-25 US disclosed
US-20070021509-A1 Phosphate transport inhibitors JOZEFIAK THOMAS H 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021509-A1 Phosphate transport inhibitors SLC34A2, SLC34A1, SLC20A1 CCR9 4370/4885SLC10A6 10/4885SLC10A2 81/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.