SLC20A1

Sodium-dependent phosphate transporter 1 · Q8WUM9 · SLC20A1 on Sugi Atlas →

1,407 patent compounds predicted against SLC20A1, 838 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL267024 SCHEMBL267024 1.00 1/20
SCHEMBL267025 SCHEMBL267025 1.00 1/20
SCHEMBL7126685 SCHEMBL7126685 0.83 1/20
SCHEMBL267842 SCHEMBL267842 0.80 1/20
SCHEMBL267843 SCHEMBL267843 0.80 1/20
SCHEMBL267856 SCHEMBL267856 0.80 1/20
SCHEMBL267857 SCHEMBL267857 0.80 1/20
SCHEMBL267924 SCHEMBL267924 0.79 1/20
SCHEMBL267925 SCHEMBL267925 0.79 1/20
SCHEMBL268319 SCHEMBL268319 0.78 1/20
SCHEMBL268320 SCHEMBL268320 0.78 1/20
SCHEMBL274252 SCHEMBL274252 0.78 1/20
SCHEMBL266512 SCHEMBL266512 0.76 1/20
SCHEMBL266513 SCHEMBL266513 0.76 1/20
SCHEMBL267960 SCHEMBL267960 0.76 1/20
SCHEMBL267961 SCHEMBL267961 0.76 1/20
SCHEMBL267826 SCHEMBL267826 0.75 1/20
SCHEMBL267827 SCHEMBL267827 0.75 1/20
SCHEMBL274075 SCHEMBL274075 0.75 1/20
SCHEMBL7120286 SCHEMBL7120286 0.74 1/20

Clinical trials — most relevant to SLC20A1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Age on the Renal Clearance of Adefovir PHASE4WITHDRAWN
Study of the Anti-FGF23 Antibody, Burosumab, in Adults With XLH PHASE3COMPLETED
Applying Proton Pump Inhibitor to Prevent and Treat Acute Fluctuating Hearing Loss in Patients With SLC26A4 Mutation PHASE2/PHASE3UNKNOWN
Study to Evaluate the Efficacy and Safety of PT20 in Subjects With Hyperphosphataemia and Dialysis Dependent Chronic Kidney Disease PHASE2COMPLETED
Healthy Combine Study PHASE1COMPLETED
Statin Therapy to Improve Medication Adherence PHASE1COMPLETED
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters EARLY_PHASE1COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Cardiovascular Effects of Empagliflozine nanUNKNOWN
Oxalate and Citrate in Humans - Response to Citrate nanRECRUITING
The Effectiveness and Safety of Calcium Carbonate in Chronic Kidney Disease With Normophosphatemia nanCOMPLETED
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital nanUNKNOWN
Sodium Transport: Genetics and Hypertension nanCOMPLETED
Calcitonin for Treating X-linked Hypophosphatemia nanCOMPLETED
POTASSIUM-RICH SALT SUBSTITUTES IN KIDNEY TRANSPLANT RECIPIENTS nanNOT_YET_RECRUITING
Oxalate and Citrate nanRECRUITING
Genetic Variations That Increase the Risk for Calcium Kidney Stones: a Family-based Study nanCOMPLETED
Lithium Countertransport and Blood Pressure In CARDIA and TOMHS nanCOMPLETED
Blood Pressure Control in Juveniles - Longitudinal Study nanCOMPLETED
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts nanCOMPLETED
Epidemiology of Gout in French Polynesia nanCOMPLETED
Studying Phosphorus Metabolism nanCOMPLETED
Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate Metabolism nanNOT_YET_RECRUITING
Biological Collection of Kidney Cells nanUNKNOWN
Bile Acid Effects in Fetal Arrhythmia Study nanUNKNOWN
Cardiorenal Risk Stratification Pilot Study nanUNKNOWN
Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management nanUNKNOWN
Impact of Polymorphisms of OAT1, OAT3, and OCT2 on Transportation of Potential Nephrotoxic Drugs nanCOMPLETED
Kidney-protective Intervention With Salt Substitute After Kidney Tumor Surgery nanRECRUITING
Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a SLC20A1 binder may also engage these)

ProteinNameSimilarity
O97596 1.000 O97596 →
Q5R9L5 1.000 Q5R9L5 →
Q28E01 1.000 Q28E01 →
Q9JJP0 1.000 Q9JJP0 →
Q61609 1.000 Q61609 →
Q6PB26 1.000 Q6PB26 →
Q5BL44 1.000 Q5BL44 →
SLC20A2 Sodium-dependent phosphate transporter 2 0.999 landscape →
Q6PFM1 0.998 Q6PFM1 →
Q5XHF9 0.998 Q5XHF9 →
Q95L97 0.996 Q95L97 →
Q68F35 0.996 Q68F35 →
Q80UP8 0.995 Q80UP8 →
A1A4I1 0.995 A1A4I1 →
Q9ES44 0.995 Q9ES44 →
Q6NV12 0.994 Q6NV12 →
Q63488 0.993 Q63488 →
Q27960 0.983 Q27960 →
Q9JIS8 0.981 Q9JIS8 →
Q5REV9 0.980 Q5REV9 →
Q924N4 0.980 Q924N4 →
P15710 0.979 P15710 →
Q9DBP0 0.979 Q9DBP0 →
Q9UHW9 0.977 Q9UHW9 →
Q5DTL9 0.977 Q5DTL9 →
Q923J4 0.977 Q923J4 →
O88343 0.977 O88343 →
SLC12A5 Solute carrier family 12 member 5 0.977 landscape →
Q9JJ09 0.977 Q9JJ09 →
Q5RK27 0.977 Q5RK27 →