Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29489567 | 0.89 | NPC1 (0.71) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL110113 | 0.89 | NPC1 (0.71) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL13550715 | 0.81 | NPC1 (0.64) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL10424691 | 0.80 | NPC1 (0.55) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL9264904 | 0.79 | NPC1 (0.55) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL2602710 | 0.79 | NPC1 (0.53) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL13138888 | 0.79 | NPC1 (0.57) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL21300041 | 0.77 | NPC1 (0.59) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL10598824 | 0.77 | NPC1 (1.00) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL7544994 | 0.77 | NPC1 (0.51) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166659-B2 | Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-7157586-B2 | Bloom-resistant benzotriazole UV absorbers and compositions stabilized therewith | CIBA SPECIALTY CHEMCIALS CORPORATION (US) | 2007-01-02 | — | — | US | disclosed |