Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 16/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301705 | 0.92 | SOAT1 (0.54) | SOAT1ALDH1A1MAPK1 | |
| SCHEMBL4516627 | 0.88 | SOAT1 (0.74) | SOAT1CETPKDM4EALDH1A1MAPT | |
| SCHEMBL6283739 | 0.88 | SOAT1 (0.60) | SOAT1CETPKDM4EALDH1A1MAPT | |
| SCHEMBL5623843 | 0.88 | SOAT1 (0.73) | SOAT1 | |
| SCHEMBL6282761 | 0.87 | SOAT1 (0.65) | SOAT1 | |
| Hydrochloric Acid SCHEMBL6654764 | 0.86 | SOAT1 (0.64) | SOAT1 | |
| SCHEMBL6280562 | 0.86 | SOAT1 (0.58) | SOAT1KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL5622111 | 0.86 | SOAT1 (0.50) | SOAT1ALDH1A1MAPT | |
| SCHEMBL4513155 | 0.85 | SOAT1 (0.50) | SOAT1CETPKDM4EALDH1A1MAPT | |
| SCHEMBL6280584 | 0.85 | SOAT1 (0.63) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163944-B2 | Cyclic diamine compound and pharmaceutical containing the same | KOWA CO., LTD. (JP) | 2007-01-16 | — | — | US | disclosed |