Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 15/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4529809 | 0.94 | SOAT1 (0.49) | SOAT1CETPALDH1A1MAPTMAPK1 | |
| SCHEMBL4530498 | 0.86 | SOAT1 (0.67) | SOAT1ALDH1A1CYP1A2CYP3A4GAA | |
| SCHEMBL14601907 | 0.85 | SOAT1 (0.56) | SOAT1CETPKDM4EALDH1A1MAPT | |
| SCHEMBL301705 | 0.83 | SOAT1 (0.54) | SOAT1ALDH1A1MAPK1 | |
| SCHEMBL4516627 | 0.82 | SOAT1 (0.74) | SOAT1CETPKDM4EALDH1A1MAPT | |
| SCHEMBL6283739 | 0.82 | SOAT1 (0.60) | SOAT1CETPKDM4EALDH1A1MAPT | |
| SCHEMBL5623843 | 0.82 | SOAT1 (0.73) | SOAT1 | |
| SCHEMBL6282761 | 0.81 | SOAT1 (0.65) | SOAT1 | |
| Hydrochloric Acid SCHEMBL6654764 | 0.81 | SOAT1 (0.64) | SOAT1 | |
| SCHEMBL6280562 | 0.81 | SOAT1 (0.58) | SOAT1KDM4EALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560547-B2 | Hydroxyalkyl cyclic diamine compounds | KOWA CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| US-20070088159-A1 | HYDROXYALKYL CYCLIC DIAMINE COMPOUNDS | KOWA CO., LTD. (JP) | 2007-04-19 | — | — | US | disclosed |
| US-7176306-B2 | Hydroxyalkyl cyclic diamine compound | KOWA CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| EP-1571144-A1 | HYDROXYALKYLATED CYCLIC DIAMINE COMPOUND | Kowa Co., Ltd. (JP) | 2005-09-07 | — | — | EP | disclosed |
| US-20040176593-A1 | Hydroxyalkyl cyclic diamine compound | KOWA CO., LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176593-A1 | Hydroxyalkyl cyclic diamine compound | DDC, AOC1, ODC1 | SOAT1 1314/4885CETP 2440/4885KDM4E 1630/4885 |
| US-20070088159-A1 | HYDROXYALKYL CYCLIC DIAMINE COMPOUNDS | HDHD5, DDC, DDT | SOAT1 1023/4885CETP 3068/4885KDM4E 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.