Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | RELA | Q04206 | 4/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352525 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRANPEPERAP2RRM1 | |
| SCHEMBL28667034 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TSHRANPEPERAP2RRM1 | |
| SCHEMBL1459003 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TSHRANPEPERAP2RRM1 | |
| SCHEMBL11826637 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TSHRANPEPERAP2RRM1 | |
| SCHEMBL11830992 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRANPEPERAP2RRM1 | |
| SCHEMBL16429465 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRRRM1RELAGNAI3 | |
| SCHEMBL6429352 | 0.86 | ALDH1A1 (0.50) | ALDH1A1TSHRANPEPERAP2RRM1 | |
| SCHEMBL9329694 | 0.83 | PPARA (0.45) | ALDH1A1TSHR | |
| SCHEMBL1019696 | 0.83 | PLA2G1B (0.56) | ALDH1A1TSHRPLA2G1BPLA2G2AS1PR2 | |
| SCHEMBL11055261 | 0.83 | PLA2G1B (0.56) | ALDH1A1TSHRPLA2G1BPLA2G2AS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475534-A1 | COMPOSITIONS AND METHODS FOR PRODUCING POLY-AMINOFUNCTIONALIZED POLYMERIZATION INITIATORS AND CORRESPONDING POLYMERS | Bridgestone Corporation (JP) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011031943-A1 | COMPOSITIONS AND METHODS FOR PRODUCING POLY-AMINOFUNCTIONALIZED POLYMERIZATION INITIATORS AND CORRESPONDING POLYMERS | BRIDGESTONE CORPORATION (JP) | 2011-03-17 | — | — | WO | disclosed |