SCHEMBL14602719

SCHEMBL14602719

COc1ccc(S(=O)(=O)N(CC(C)C)C[C@@H](O)C(N)Cc2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SPPL2A Q8TCT8 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1058690 1.00 SPPL2A (0.69) SPPL2A
SCHEMBL7905239 1.00 SPPL2A (0.69) SPPL2A
SCHEMBL15355882 0.94 SPPL2A (0.61) SPPL2A
SCHEMBL28738327 0.94 SPPL2A (0.60) SPPL2A
SCHEMBL28628356 0.94 SPPL2A (0.60) SPPL2A
SCHEMBL28628359 0.94 SPPL2A (0.60) SPPL2A
SCHEMBL28628358 0.94 SPPL2A (0.60) SPPL2A
SCHEMBL13174129 0.93 SPPL2A (0.61) SPPL2A
SCHEMBL5945539 0.93 SPPL2A (0.61) SPPL2A
SCHEMBL4911140 0.90 SPPL2A (0.76) SPPL2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7157489-B2 HIV protease inhibitors THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2007-01-02 — — US disclosed
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