Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1058690 | 1.00 | SPPL2A (0.69) | SPPL2A | |
| SCHEMBL14602719 | 1.00 | SPPL2A (0.69) | SPPL2A | |
| SCHEMBL15355882 | 0.94 | SPPL2A (0.61) | SPPL2A | |
| SCHEMBL28738327 | 0.94 | SPPL2A (0.60) | SPPL2A | |
| SCHEMBL28628358 | 0.94 | SPPL2A (0.60) | SPPL2A | |
| SCHEMBL28628359 | 0.94 | SPPL2A (0.60) | SPPL2A | |
| SCHEMBL28628356 | 0.94 | SPPL2A (0.60) | SPPL2A | |
| SCHEMBL13174129 | 0.93 | SPPL2A (0.61) | SPPL2A | |
| SCHEMBL5945539 | 0.93 | SPPL2A (0.61) | SPPL2A | |
| SCHEMBL4911140 | 0.90 | SPPL2A (0.76) | SPPL2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230630-A | Triptolide derivative and application thereof | 郑州人民医院(郑州人民医院医疗管理中心) | 2022-03-25 | — | — | CN | disclosed |
| WO-2010075887-A1 | METHODS AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF HEXAHYDROFURO[2,3-B]FURAN-3-OL | OXYRANE (UK) LIMITED (GB) | 2010-07-08 | — | — | WO | disclosed |
| US-20100168422-A1 | METHODS AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF HEXAHYDROFURO [2,3-B]FURAN-3-OL | CLINTON HEALTH ACCESS INITIATIVE, INC. | 2010-07-01 | — | — | US | disclosed |
| US-20100168422-A1 | METHODS AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF HEXAHYDROFURO [2,3-B]FURAN-3-OL | CLINTON HEALTH ACCESS INITIATIVE, INC. | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168422-A1 | METHODS AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF HEXAHYDROFURO [2,3-B]FURAN-3-OL | FDPS, DHFR, AKR7A2 | SPPL2A 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.