SCHEMBL1460416

SCHEMBL1460416

NC(=O)c1ccc(-c2ccc(C(=O)n3c4ccc3cc4)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MKNK1 Q9BUB5 11/20 0.46
MKNK2 Q9HBH9 11/20 0.46
CYP17A1 P05093 1/20 0.43
BRD4 O60885 1/20 0.42
BRD9 Q9H8M2 1/20 0.42
MAP4K4 O95819 2/20 0.42
ERN1 O75460 1/20 0.42
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42
PARP15 Q460N3 1/20 0.42
PARP14 Q460N5 1/20 0.42
PARP10 Q53GL7 1/20 0.42
PARP16 Q8N5Y8 1/20 0.42
PARP11 Q9NR21 1/20 0.42
PARP4 Q9UKK3 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL174536 0.94 PARP10 (0.46) CA12CA1CA2CA9CA14
Hydrochloric Acid SCHEMBL27677598 0.92 PARP10 (0.45) CA12CA1CA2CA9CA14
SCHEMBL28344986 0.92 PARP10 (0.45) CA12CA1CA2CA9CA14
Urea SCHEMBL11673195 0.92 PARP10 (0.45) CA12CA1CA2CA9CA14
Water SCHEMBL27561730 0.92 PARP10 (0.45) CA12CA1CA2CA9CA14
Hydrazine SCHEMBL28084706 0.92 PARP10 (0.45) CA12CA1CA2CA9CA14
Benzene SCHEMBL28239358 0.90 MAPT (0.54) CA1CA2MKNK1MKNK2ALDH1A1
Oxalic Acid SCHEMBL27509979 0.88 PARP1 (0.46) CA12CA1CA2CA9CA14
Terephthalic Acid SCHEMBL28640934 0.86 PARP10 (0.53) CA12CA1CA2CA9CA14
SCHEMBL27673550 0.86 PARP10 (0.53) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4839112-A STACKING PHTHOCYANINE STRONG BRONSTED ACID; SHAPING; SOLIDIFICATION NORTHWESTERN UNIVERSITY (US) 1989-06-13 US claimed
US-4622170-A PORPHYRAZINE, POLYAMIDE AND BRONSTED ACID NORTHWESTERN UNIVERSITY (US) 1986-11-11 US claimed
US-4563301-A COFACIALLY STACKED NORTHWESTERN UNIVERSITY (US) 1986-01-07 US claimed
CN-115191059-B Separator for lithium ion secondary battery and lithium ion secondary battery 日本高度纸工业株式会社 2023-09-29 CN disclosed
EP-2486229-B1 APPARATUSES AND METHODS OF MANUFACTURING OILFIELD MACHINES MI LLC (US) 2021-09-29 EP disclosed
US-9994979-B2 Lightweight, cut and/or abrasion resistant garments, and related protective wear SUPREME CORPORATION (US) 2018-06-12 US disclosed
US-20120245014-A1 APPARATUSES AND METHODS OF MANUFACTURING OILFIELD MACHINES M-I L.L.C. 2012-09-27 US disclosed
US-20120207966-A1 BALLISTIC LAMINATE STRUCTURE TENCATE ADVANCED ARMOR USA, INC. (US) 2012-08-16 US disclosed
EP-2486229-A2 APPARATUSES AND METHODS OF MANUFACTURING OILFIELD MACHINES M.I L.L, C. (US) 2012-08-15 EP disclosed
WO-2011044227-A2 APPARATUSES AND METHODS OF MANUFACTURING OILFIELD MACHINES M-I L.L.C. (US) 2011-04-14 WO disclosed
WO-2011028746-A1 LIGHTWEIGHT, CUT AND/OR ABRASION RESISTANT GARMENTS, AND RELATED PROTECTIVE WEAR KOLMES NATHANIEL H (US) 2011-03-10 WO disclosed
WO-1991010409-A1 CUT RESISTANT PROTECTIVE GLOVE ALLIED-SIGNAL INC. (US) 1991-07-25 WO disclosed
WO-1991007633-A1 BALLISTIC RESISTANT COMPOSITE ARMOR HAVING IMPROVED MULTIPLE-HIT CAPABILITY ALLIED-SIGNAL INC. (US) 1991-05-30 WO disclosed
US-4839112-A STACKING PHTHOCYANINE STRONG BRONSTED ACID; SHAPING; SOLIDIFICATION NORTHWESTERN UNIVERSITY (US) 1989-06-13 US disclosed
US-4622170-A PORPHYRAZINE, POLYAMIDE AND BRONSTED ACID NORTHWESTERN UNIVERSITY (US) 1986-11-11 US disclosed
EP-0182784-A1 COMPOSITE SURGICAL SUTURES BIORESEARCH INC. (US) 1986-06-04 EP disclosed
US-4563300-A PORPHYRAZINE AND AROMATIC POLYAMIDE NORTHWESTERN UNIVERSITY (US) 1986-01-07 US disclosed
US-4563301-A COFACIALLY STACKED NORTHWESTERN UNIVERSITY (US) 1986-01-07 US disclosed
WO-1986000020-A1 COMPOSITE SURGICAL SUTURES BIORESEARCH INC. (US) 1986-01-03 WO disclosed
US-RE30352-E AMIDE OR UREA CONTAINING SALT, SULFURIC ACID, HYDROFLUORIC ACID, OR HALO- OR METHANESULFONIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed