SCHEMBL1460641

SCHEMBL1460641

NC(Cc1c[nH]c2cccc(O)c12)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.68
KDM4E B2RXH2 4/20 0.68
MAPT P10636 4/20 0.68
MEN1 O00255 4/20 0.68
LMNA P02545 3/20 0.68
BLM P54132 3/20 0.68
PMP22 Q01453 3/20 0.68
TSHR P16473 2/20 0.68
HIF1A Q16665 2/20 0.68
MPO P05164 1/20 0.68
ALDH1A1 P00352 3/20 0.62
GAA P10253 2/20 0.62
POLB P06746 2/20 0.62
THRB P10828 2/20 0.62
RECQL P46063 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
DNMT1 P26358 1/20 0.62
CASP6 P55212 1/20 0.62
MCL1 Q07820 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18029267 1.00 KMT2A (0.68) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL30084863 1.00 KMT2A (0.68) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL1114867 1.00 KMT2A (0.68) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL7480432 0.86 KMT2A (0.63) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL30356567 0.86 KMT2A (0.63) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL27917618 0.86 KMT2A (0.63) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL7480435 0.86 KMT2A (0.63) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL458570 0.86 KMT2A (0.63) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL18029241 0.86 KMT2A (0.63) KMT2AKDM4EMAPTMEN1LMNA
SCHEMBL458569 0.86 KMT2A (0.63) KMT2AKDM4EMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250064783-A1 Compositions of Matter and Pharmaceutical Compositions PSILERA INC. 2025-02-27 US claimed
US-20240417764-A1 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY 2024-12-19 US claimed
EP-4426818-A2 METHODS FOR THE IMPROVED PRODUCTION OF PSILOCYBIN AND INTERMEDIATES MIAMI UNIVERSITY (US) 2024-09-11 EP claimed
EP-4426676-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-09-11 EP claimed
WO-2023081837-A9 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-03-14 WO claimed
EP-4208445-A1 HALOGENATED PSILOCYBIN DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2023-07-12 EP claimed
WO-2022150854-A9 SYSTEMS AND METHODS FOR PHARMACEUTICAL PRODUCTION OF PSILOCYBIN AND INTERMEDIATES OR SIDE PRODUCTS MIAMI UNIVERSITY (US) 2023-07-06 WO claimed
WO-2023130076-A2 TARGETS AND PATHWAYS FOR THE PRODUCTION OF ALKALOIDAL COMPOUNDS Empyrean Neuroscience, Inc. (US) 2023-07-06 WO claimed
CN-116348106-A Halogenated nupharicin derivatives and methods of use 恩维瑞克生物科学加拿大公司 2023-06-27 CN claimed
WO-2023081837-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2023-05-11 WO claimed
JP-4641942-B2 2011-03-02 JP claimed
US-20080194553-A1 compounds that are capable of increasing the serum level of insulin-like growth factor 1 (IGF-1) for the preparation of a therapeutical composition,in the form of a food supplement, for the treatment of subjects suffering from serious fatigue and exhausting symptoms, burn-out and chronic fatigue syndrome VEIJLEN N.V. (NL) 2008-08-14 US claimed
US-20070299128-A1 Use of Tryptophan Derivatives for the Specific Cytostatic Treatment of Serotonin-Producing Tumors WALTHER DIEGO 2007-12-27 US claimed
CN-1938018-A Use of compounds capable of increasing serum IGF-1 levels for the preparation of therapeutic compositions for the treatment of various disease states associated with decreased IGF-1 serum levels in humans and animals VEIJLEN LTD (AN) 2007-03-28 CN claimed
EP-1670444-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES Veijlen N.V. (AN) 2006-06-21 EP claimed
WO-2005039546-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES VEIJLEN N.V. (AN) 2005-05-06 WO claimed
EP-1368027-B1 USE OF TRYPTOPHAN DERIVATIVES FOR THE SPECIFIC CYTOSTATIC TREATMENT OF SEROTONIN-PRODUCING TUMORS MAX DELBRUECK CENTRUM (DE) 2004-08-04 EP claimed
US-20040097576-A1 Use of tryptophan derivatives for the specific cytostatic treatment of serotonin-producing tumors MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN (DE) 2004-05-20 US claimed
EP-1368027-A2 USE OF TRYPTOPHAN DERIVATIVES FOR THE SPECIFIC CYTOSTATIC TREATMENT OF SEROTONIN-PRODUCING TUMORS MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) 2003-12-10 EP claimed
WO-2002074309-A2 USE OF TRYPTOPHAN DERIVATIVES FOR THE SPECIFIC CYTOSTATIC TREATMENT OF SEROTONIN-PRODUCING TUMORS Max-Delbrück-Centrum für Molekulare Medizin (DE) 2002-09-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250064783-A1 Compositions of Matter and Pharmaceutical Compositions TPH1, HTR1B, HTR2C KMT2A 2419/4885KDM4E 2638/4885MAPT 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.