SCHEMBL14606830

SCHEMBL14606830

COc1cc(/C=C(/C(C)=O)C(=O)NC(C)=O)ccc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.76
TDP1 Q9NUW8 3/20 0.58
GAA P10253 2/20 0.58
GLO1 Q04760 5/20 0.58
ABL1 P00519 1/20 0.58
IKBKB O14920 1/20 0.54
CHUK O15111 1/20 0.54
IKBKG Q9Y6K9 1/20 0.54
APP P05067 2/20 0.52
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
TRIM24 O15164 1/20 0.51
ALDH5A1 P51649 1/20 0.51
ABAT P80404 1/20 0.51
TRIM33 Q9UPN9 1/20 0.51
SNCA P37840 4/20 0.51
CYP2D6 P10635 3/20 0.51
CYP2C9 P11712 2/20 0.51
TSHR P16473 2/20 0.51
HSD17B10 Q99714 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7523992 0.87 MAPT (1.00) MAPTTDP1GAAGLO1ABL1
SCHEMBL12394170 0.83 MAPT (0.85) MAPTTDP1GAAGLO1ABL1
SCHEMBL5597360 0.83 MAPT (0.85) MAPTTDP1GAAGLO1ABL1
SCHEMBL2252350 0.83 MAPT (0.85) MAPTTDP1GAAGLO1ABL1
SCHEMBL19432109 0.82 MAPT (0.83) MAPTTDP1GAAGLO1ABL1
SCHEMBL10821709 0.82 MAPT (0.83) MAPTTDP1GAAGLO1ABL1
SCHEMBL935705 0.80 MAPT (0.74) MAPTTDP1GAAGLO1ABL1
SCHEMBL16307895 0.80 MAPT (0.74) MAPTTDP1GAAGLO1ABL1
SCHEMBL10741104 0.80 MAPT (0.61) MAPTTDP1GAAGLO1ABL1
SCHEMBL11312156 0.80 MAPT (0.61) MAPTTDP1GAAGLO1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1441254-B1 Photothermographic material FUJIFILM CORP (JP) 2007-03-28 EP disclosed