Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | IKBKB | O14920 | 1/20 | 0.62 |
| ▸ | CHUK | O15111 | 1/20 | 0.62 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.60 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.60 |
| ▸ | ABAT | P80404 | 1/20 | 0.60 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | SNCA | P37840 | 3/20 | 0.59 |
| ▸ | APP | P05067 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16307895 | 0.97 | MAPT (0.74) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL5597202 | 0.92 | MAPT (0.68) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL6380063 | 0.87 | ALDH1A1 (0.60) | MAPTTDP1ALDH1A1APPCYP1A2 | |
| Methyl 3,4-Dimethoxybenzalmalonate SCHEMBL14462724 | 0.87 | GAA (0.73) | MAPTGLO1IKBKBCHUKIKBKG | |
| SCHEMBL7523992 | 0.85 | MAPT (1.00) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL2213640 | 0.85 | MAPT (0.77) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL934307 | 0.85 | MAPT (0.70) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL933587 | 0.85 | MAPT (0.67) | MAPTGLO1ABL1IKBKBCHUK | |
| SCHEMBL20162241 | 0.85 | TOP2A (0.62) | MAPTGLO1ABL1ALDH1A1GAA | |
| SCHEMBL168150 | 0.85 | MAPT (0.67) | MAPTGLO1ABL1IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
| WO-2011006566-A2 | MONOMETHOXY-HYDROXY-BENZYLMALONATES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | WO | disclosed |
| US-20070010579-A1 | Copper salts of organic acids and use thereof as fungicides | ISARGO S.P.A. (IT) | 2007-01-11 | — | — | US | disclosed |
| EP-1633190-A1 | COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES | ISAGRO S.p.A. (IT) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004103074-A1 | COPPER SALTS OF ORGANIC ACIDS AND USE THEREOF AS FUNGICIDES | ISAGRO S.P.A. (IT) | 2004-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | MAPT 1864/4885GLO1 255/4885ABL1 4102/4885 |
| US-20070010579-A1 | Copper salts of organic acids and use thereof as fungicides | AOC3, AOC2, AOC1 | MAPT 679/4885GLO1 279/4885ABL1 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.