SCHEMBL14608751

SCHEMBL14608751

c1ccc(-c2c3ccc(N(c4ccccc4)c4cccc5ccccc45)cc3c(-c3ccccc3)c3ccc(-c4ccc(N(c5ccccc5)c5cccc6ccccc56)cc4)cc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.35
ESR1 P03372 4/20 0.33
ESR2 Q92731 4/20 0.33
HSD17B1 P14061 2/20 0.33
HSD17B2 P37059 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2B6 P20813 1/20 0.33
CYP2C19 P33261 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
DHFR P00374 1/20 0.30
ACHE P22303 2/20 0.30
CYP1A1 P04798 2/20 0.30
CYP1B1 Q16678 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14516042 0.97 SIGMAR1 (0.37) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL15762753 0.97 SIGMAR1 (0.37) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL9963825 0.97 SIGMAR1 (0.37) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL2613891 0.96 SIGMAR1 (0.36) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL2613781 0.96 SIGMAR1 (0.36) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL14489459 0.96 ESR1 (0.36) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL13333604 0.96 ESR1 (0.36) SIGMAR1ESR1ESR2HSD17B1HSD17B2
SCHEMBL12014668 0.95 SIGMAR1 (0.38) SIGMAR1ESR1ESR2CYP1A2DHFR
SCHEMBL12928338 0.95 SIGMAR1 (0.38) SIGMAR1ESR1ESR2CYP1A2DHFR
SCHEMBL24638518 0.93 SIGMAR1 (0.36) SIGMAR1ESR1ESR2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007021117-A1 GREEN ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2007-02-22 WO disclosed