Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 6/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044517 | 1.00 | PTGFR (0.48) | PTGFRPTGER3ABCC4ABCB11CYP1A2 | |
| SCHEMBL1044516 | 1.00 | PTGFR (0.48) | PTGFRPTGER3ABCC4ABCB11CYP1A2 | |
| SCHEMBL1044518 | 1.00 | PTGFR (0.48) | PTGFRPTGER3ABCC4ABCB11CYP1A2 | |
| SCHEMBL3053177 | 0.93 | PTGFR (0.47) | PTGFRPTGER3ABCC4ABCB11CYP1A2 | |
| SCHEMBL1043819 | 0.93 | PTGFR (0.47) | PTGFRPTGER3ABCC4ABCB11CYP1A2 | |
| SCHEMBL1043817 | 0.93 | PTGFR (0.47) | PTGFRPTGER3ABCC4ABCB11CYP1A2 | |
| SCHEMBL1043820 | 0.93 | PTGFR (0.47) | PTGFRPTGER3ABCC4ABCB11CYP1A2 | |
| SCHEMBL1460588 | 0.93 | PTGFR (0.47) | PTGFRPTGER3ABCC4ABCB11CYP1A2 | |
| SCHEMBL1043901 | 0.90 | PTGFR (0.58) | PTGFRPTGER3ABCC4ABCB11THRB | |
| SCHEMBL1043898 | 0.90 | PTGFR (0.58) | PTGFRPTGER3ABCC4ABCB11THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032159-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | META COMESTICS, LLC (US) | 2011-03-17 | — | — | WO | disclosed |