Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 17/20 | 0.58 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043901 | 1.00 | PTGFR (0.58) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL1043903 | 1.00 | PTGFR (0.58) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL1461634 | 1.00 | PTGFR (0.58) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL1044517 | 0.90 | PTGFR (0.48) | PTGFRPTGER3ABCC4ABCB11THRB | |
| SCHEMBL1044516 | 0.90 | PTGFR (0.48) | PTGFRPTGER3ABCC4ABCB11THRB | |
| SCHEMBL1044518 | 0.90 | PTGFR (0.48) | PTGFRPTGER3ABCC4ABCB11THRB | |
| SCHEMBL1460919 | 0.90 | PTGFR (0.48) | PTGFRPTGER3ABCC4ABCB11THRB | |
| SCHEMBL1047178 | 0.90 | PTGFR (0.60) | PTGFRPTGER3ABCC4ABCB11TBXA2R | |
| SCHEMBL1043819 | 0.90 | PTGFR (0.47) | PTGFRPTGER3ABCC4ABCB11 | |
| SCHEMBL1460588 | 0.90 | PTGFR (0.47) | PTGFRPTGER3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | LUBIT BEVERLY W | 2011-01-06 | — | — | US | claimed |
| US-20100074857-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | LIPKIN PAMELA | 2010-03-25 | — | — | US | claimed |
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | LUBIT BEVERLY W | 2011-01-06 | — | — | US | disclosed |
| WO-2010039535-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | META COSMETICS, LLC (US) | 2010-04-08 | — | — | WO | disclosed |
| US-20100074857-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | LIPKIN PAMELA | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110002866-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | PGF, PTGS1, PTGS2 | PTGFR 5/4885PTGER3 75/4885ABCC4 2628/4885 |
| US-20100074857-A1 | COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS | PTGER1, PGF, PTGER2 | PTGFR 6/4885PTGER3 9/4885ABCC4 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.