Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5298861 | 0.99 | TRPM8 (0.56) | TRPM8RAB9AKMT2ALMNAMAPT | |
| SCHEMBL14610217 | 0.98 | TRPM8 (0.60) | TRPM8RAB9AKMT2ALMNAMAPT | |
| SCHEMBL14610073 | 0.95 | TRPM8 (0.58) | TRPM8RAB9AKMT2ALMNAMAPT | |
| SCHEMBL14610199 | 0.95 | TRPM8 (0.52) | TRPM8RAB9AKMT2ALMNAMAPT | |
| SCHEMBL14610620 | 0.94 | TRPM8 (0.59) | TRPM8RAB9AKMT2ALMNAMAPT | |
| SCHEMBL14609991 | 0.93 | TRPM8 (0.52) | TRPM8RAB9AKMT2ALMNAMAPT | |
| SCHEMBL14610001 | 0.92 | TRPM8 (0.65) | TRPM8KDM4ENPC1LPAR1HTT | |
| SCHEMBL14610251 | 0.92 | TRPM8 (0.60) | TRPM8RAB9AKMT2ALMNAMAPT | |
| SCHEMBL14610000 | 0.91 | TRPM8 (0.50) | TRPM8MAPTLPAR1SLC1A5 | |
| SCHEMBL14610207 | 0.90 | TRPM8 (0.57) | TRPM8RAB9AKMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017093-A1 | SUBSTITUTED 2-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |