Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610119 | 0.78 | HTR1D (0.43) | F2HTR6PRSS1PRSS2PRSS3 | |
| SCHEMBL3533435 | 0.78 | HTR6 (0.38) | F2HTR6PRSS1PRSS2PRSS3 | |
| SCHEMBL14610346 | 0.77 | SLC6A4 (0.44) | HTR6MTNR1AMTNR1B | |
| SCHEMBL14610408 | 0.77 | KDM4E (0.39) | F2PRSS1PRSS2PRSS3MTNR1A | |
| SCHEMBL14610399 | 0.75 | GCGR (0.51) | ESR1ESR2 | |
| SCHEMBL14610349 | 0.75 | GCGR (0.52) | ESR1ESR2 | |
| SCHEMBL14610197 | 0.75 | KDM4E (0.46) | MTNR1AMTNR1BNPY5R | |
| SCHEMBL14610129 | 0.74 | CA12 (0.45) | F2HTR6CA1CA9 | |
| SCHEMBL14610113 | 0.73 | CA12 (0.40) | F2HTR6CA1CA9MTNR1A | |
| SCHEMBL14610421 | 0.72 | HTR1D (0.43) | F2HTR6PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021711-A2 | SUBSTITUTED-3-SULFONYLINDAZOLE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2007-02-22 | — | — | WO | disclosed |