Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14569599 | 1.00 | EPHX2 (0.48) | EPHX2LTA4HALDH1A1SMN1; SMN2GAA | |
| SCHEMBL14557976 | 0.87 | DPP4 (0.42) | EPHX2LTA4HALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL14557858 | 0.87 | DPP4 (0.42) | EPHX2LTA4HALDH1A1SMN1; SMN2TRPV1 | |
| SCHEMBL14569591 | 0.82 | CYP2D6 (0.45) | ALDH1A1SMN1; SMN2TRPV1RAB9AKMT2A | |
| SCHEMBL5152852 | 0.81 | NPC1 (0.53) | LTA4HALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14569546 | 0.79 | HRH3 (0.48) | EPHX2ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL14569628 | 0.78 | EPHX2 (0.41) | EPHX2PREPSSTR5 | |
| SCHEMBL14569506 | 0.78 | ALDH1A1 (0.50) | LTA4HALDH1A1RAB9ANPC1 | |
| SCHEMBL14569706 | 0.78 | EPHX2 (0.40) | EPHX2ALDH1A1SMN1; SMN2MEN1RAB9A | |
| SCHEMBL14569600 | 0.77 | DPP4 (0.41) | EPHX2LTA4HMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179819-B2 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-02-20 | — | — | US | disclosed |