SCHEMBL14610951

SCHEMBL14610951

CNC1CCN(CCc2c(F)cnc3ccc(OC)nc23)CC1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 11/20 0.66
SLC2A1 P11166 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27061392 0.89 KCNH2 (0.62) KCNH2SLC2A1
SCHEMBL5746094 0.88 KCNH2 (0.61) KCNH2SLC2A1
SCHEMBL14610957 0.85 KCNH2 (0.59) KCNH2SLC2A1
SCHEMBL32667729 0.85 KCNH2 (0.58) KCNH2SLC2A1
SCHEMBL27062102 0.85 KCNH2 (0.58) KCNH2SLC2A1
SCHEMBL14610963 0.85 KCNH2 (0.69) KCNH2SLC2A1
SCHEMBL14087091 0.83 KCNH2 (0.58) KCNH2SLC2A1
SCHEMBL27035900 0.82 KCNH2 (0.56) KCNH2SLC2A1
SCHEMBL27062134 0.82 KCNH2 (0.56) KCNH2SLC2A1
SCHEMBL3271529 0.82 SLC2A1 (0.60) KCNH2SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007016610-A2 ANTIBACTERIAL AGENTS GLAXO GROUP LIMITED (GB) 2007-02-08 WO disclosed