Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27062102 | 1.00 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL27061392 | 0.88 | KCNH2 (0.62) | KCNH2SLC2A1 | |
| SCHEMBL5746094 | 0.87 | KCNH2 (0.61) | KCNH2SLC2A1 | |
| SCHEMBL14610951 | 0.85 | KCNH2 (0.66) | KCNH2SLC2A1 | |
| SCHEMBL32667417 | 0.84 | KCNH2 (0.53) | KCNH2SLC2A1 | |
| SCHEMBL32667819 | 0.84 | KCNH2 (0.53) | KCNH2SLC2A1 | |
| SCHEMBL14087091 | 0.82 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL27062134 | 0.82 | KCNH2 (0.56) | KCNH2SLC2A1 | |
| SCHEMBL27035900 | 0.82 | KCNH2 (0.56) | KCNH2SLC2A1 | |
| SCHEMBL3271529 | 0.81 | SLC2A1 (0.60) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260027101-A1 | BACTERIAL TOPOISOMERASE INHIBITORS | OHIO STATE INNOVATION FOUNDATION (US) | 2026-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260027101-A1 | BACTERIAL TOPOISOMERASE INHIBITORS | TOP1, TOP2A, TOP2B | KCNH2 2730/4885SLC2A1 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.