Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1267116 | 0.83 | ALDH1A1 (0.54) | PDE3BPDE3AALDH1A1LMNARAB9A | |
| SCHEMBL620000 | 0.82 | HTT (0.50) | PDE3BPDE3AALDH1A1LMNARAB9A | |
| SCHEMBL3926846 | 0.81 | HTT (0.42) | PDE3BPDE3AALDH1A1LMNARAB9A | |
| SCHEMBL13948583 | 0.81 | HPGD (0.43) | PDE3BPDE3AALDH1A1LMNARAB9A | |
| SCHEMBL5521745 | 0.79 | PDE3B (0.35) | PDE3BPDE3AALDH1A1LMNARAB9A | |
| SCHEMBL5749110 | 0.78 | HTT (0.40) | PDE3BPDE3AALDH1A1LMNARAB9A | |
| SCHEMBL21972303 | 0.77 | MEN1 (0.52) | PDE3BPDE3AALDH1A1HPGDPOLB | |
| SCHEMBL21972302 | 0.75 | POLB (0.40) | PDE3BPDE3AALDH1A1LMNARAB9A | |
| SCHEMBL4142652 | 0.74 | PDE3B (0.52) | PDE3BPDE3AALDH1A1LMNARAB9A | |
| SCHEMBL21972305 | 0.72 | HSD17B10 (0.42) | ALDH1A1RAB9ANPC1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |