Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094243 | 0.84 | SLC6A3 (0.59) | SLC6A2SLC6A4SLC6A3MAPTPKM | |
| SCHEMBL6829116 | 0.76 | SLC6A3 (0.74) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8498107 | 0.76 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL10262984 | 0.74 | SLC6A3 (0.56) | SLC6A2SLC6A4SLC6A3MAPTPKM | |
| SCHEMBL4757346 | 0.73 | MAPT (0.46) | SLC6A2SLC6A4SLC6A3MAPTPKM | |
| SCHEMBL11105288 | 0.70 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL10964462 | 0.70 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL10964465 | 0.70 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL11105295 | 0.70 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL10964456 | 0.70 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016643-A2 | A METHOD FOR EXTENDING LONGEVITY USING NPC1L1 ANTAGONISTS | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2007-02-08 | — | — | WO | disclosed |