Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045839 | 0.90 | METTL3 (0.79) | METTL3MAPTGAATP53KDM4E | |
| SCHEMBL1045841 | 0.90 | METTL3 (0.79) | METTL3MAPTGAATP53KDM4E | |
| SCHEMBL14611504 | 0.88 | METTL3 (0.66) | METTL3MAPTGAATP53KDM4E | |
| SCHEMBL1041270 | 0.84 | METTL3 (0.77) | METTL3MAPTGAATP53KDM4E | |
| SCHEMBL1041271 | 0.84 | METTL3 (0.77) | METTL3MAPTGAATP53KDM4E | |
| SCHEMBL11948687 | 0.83 | METTL3 (0.69) | METTL3MAPTGAATP53PLA2G4A | |
| SCHEMBL4366550 | 0.83 | METTL3 (0.78) | METTL3MAPTGAATP53KDM4E | |
| SCHEMBL29874917 | 0.83 | METTL3 (0.68) | METTL3MAPTGAATP53KDM4E | |
| SCHEMBL1042817 | 0.83 | METTL3 (0.68) | METTL3MAPTGAATP53KDM4E | |
| SCHEMBL1042819 | 0.83 | METTL3 (0.68) | METTL3MAPTGAATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176220-B2 | 4-oxoquinoline compound and use thereof as pharmaceutical agent | JAPAN TOBACCO INC. (JP) | 2007-02-13 | — | — | US | disclosed |