Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21546124 | 0.92 | KMT2A (0.37) | F10KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL19275854 | 0.92 | KMT2A (0.46) | KMT2AMEN1TAAR1PLA2G4B | |
| SCHEMBL21575565 | 0.90 | KMT2A (0.43) | PARP1KMT2AMEN1TAAR1PARP10 | |
| SCHEMBL29530487 | 0.89 | THRA (0.36) | F10KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL14798786 | 0.89 | THRA (0.36) | F10KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL19275855 | 0.88 | KMT2A (0.39) | F10KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL19275852 | 0.87 | KMT2A (0.40) | F10KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL21546137 | 0.87 | PARP1 (0.36) | PARP1F10KMT2AMEN1TAAR1 | |
| SCHEMBL14611467 | 0.86 | SMN1; SMN2 (0.45) | KMT2AMEN1TAAR1ALDH1A1MAPK1 | |
| SCHEMBL21546126 | 0.86 | F10 (0.42) | F10KMT2AMEN1TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926829-B2 | LABELLED MODIFIED GUANINE-CONTAINING NUCLEOSIDES AND NUCLEOTIDES COMPRISING A FLUOROPHORE ATTACHED TO THE BASE THROUGH A LINKING GROUP COMPRISING A POLYETHYLENE GLYCOL SPACING GROUP AND METHODS FOR THEIR USE | ILLUMINA CAMBRIDGE LTD (GB) | 2017-07-19 | — | — | EP | disclosed |
| EP-1926829-B1 | LABELLED MODIFIED GUANINE-CONTAINING NUCLEOSIDES AND NUCLEOTIDES COMPRISING A FLUOROPHORE ATTACHED TO THE BASE THROUGH A LINKING GROUP COMPRISING A POLYETHYLENE GLYCOL SPACING GROUP AND METHODS FOR THEIR USE | ILLUMINA CAMBRIDGE LTD (GB) | 2014-08-06 | — | — | EP | disclosed |
| WO-2007020457-A2 | LABELLED MODIFIED GUANINE- CONTAINING NUCLEOSIDES AND NUCLEOTIDES COMPRISING A FLUOROPHORE ATTACHED TO THE BASE THROUGH A LINKING GROUP COMPRISING A POLYETHYLENE GLYCOL SPACING GROUP AND METHODS FOR THEIR USE | SOLEXA LIMITED (GB) | 2007-02-22 | — | — | WO | disclosed |