Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1043828 | 0.92 | KMT2A (0.42) | KMT2AMAPTLMNASTAT3TDP1 | |
| SCHEMBL13447868 | 0.86 | KMT2A (0.42) | KMT2AMAPTLMNASTAT3TDP1 | |
| SCHEMBL14611804 | 0.86 | KMT2A (0.38) | KMT2AMAPTLMNASTAT3TDP1 | |
| SCHEMBL1046063 | 0.79 | CMA1 (0.38) | KMT2AMAPTLMNASTAT3TDP1 | |
| SCHEMBL1045833 | 0.79 | CHRM1 (0.45) | MAPTLMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL11957341 | 0.78 | CMA1 (0.39) | KMT2AMAPTLMNASTAT3TDP1 | |
| SCHEMBL1432398 | 0.77 | KMT2A (0.49) | KMT2AMAPTLMNASTAT3TDP1 | |
| SCHEMBL3246619 | 0.75 | MAPT (0.36) | MAPTSMN1; SMN2 | |
| SCHEMBL11193162 | 0.74 | STAT3 (0.61) | KMT2AMAPTLMNASTAT3TDP1 | |
| SCHEMBL11956884 | 0.73 | MAPT (0.37) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176220-B2 | 4-oxoquinoline compound and use thereof as pharmaceutical agent | JAPAN TOBACCO INC. (JP) | 2007-02-13 | — | — | US | disclosed |