Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11956944 | 0.82 | SLC22A12 (0.36) | MAPTSLC22A12P2RX7PKM | |
| SCHEMBL11956951 | 0.81 | METTL3 (0.34) | SLC22A12P2RX7PKM | |
| SCHEMBL11956461 | 0.81 | METTL3 (0.34) | SLC22A12P2RX7PKM | |
| SCHEMBL13862196 | 0.78 | ALDH1A1 (0.36) | MAPTSLC22A12SMN1; SMN2 | |
| SCHEMBL1045833 | 0.78 | CHRM1 (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL1043828 | 0.78 | KMT2A (0.42) | MAPT | |
| SCHEMBL3246619 | 0.76 | MAPT (0.36) | MAPTSLC22A12SMN1; SMN2 | |
| SCHEMBL13447868 | 0.74 | KMT2A (0.42) | MAPTSMN1; SMN2 | |
| SCHEMBL13862195 | 0.73 | ALDH1A1 (0.31) | MAPTSMN1; SMN2 | |
| SCHEMBL14611499 | 0.73 | KMT2A (0.43) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232401-B2 | Useful as an anti-HIV agent that particularly shows an anti-HIV action based on an integrase inhibitory activity; for treatment or prophylaxis of AIDS; for example, 6-(2,3-dichlorobenzyl)-1-(2-hydroxyethyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | JAPAN TOBACCO INC. (JP) | 2012-07-31 | — | — | US | disclosed |