Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045211 | 0.90 | METTL3 (0.58) | METTL3MAPTTOP1CHRM1KDM4E | |
| SCHEMBL1045210 | 0.90 | METTL3 (0.58) | METTL3MAPTTOP1CHRM1KDM4E | |
| SCHEMBL14611504 | 0.85 | METTL3 (0.66) | METTL3MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL14611503 | 0.83 | METTL3 (0.58) | METTL3MAPT | |
| SCHEMBL4372214 | 0.81 | METTL3 (0.53) | METTL3MAPTTOP1CHRM1CMA1 | |
| SCHEMBL4371645 | 0.81 | METTL3 (0.53) | METTL3MAPTTOP1CHRM1HPGD | |
| SCHEMBL25726683 | 0.80 | METTL3 (0.49) | METTL3MAPTALDH1A1RXFP1TP53 | |
| SCHEMBL14611501 | 0.79 | KMT2A (0.34) | METTL3MAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL3239826 | 0.79 | METTL3 (0.50) | METTL3MAPTALDH1A1RXFP1TP53 | |
| SCHEMBL1045282 | 0.78 | METTL3 (0.73) | METTL3MAPTTOP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176220-B2 | 4-oxoquinoline compound and use thereof as pharmaceutical agent | JAPAN TOBACCO INC. (JP) | 2007-02-13 | — | — | US | disclosed |