Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401058 | 0.87 | KMT2A (0.53) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL12864677 | 0.79 | MEN1 (0.65) | MAPTMEN1KMT2AKCNH2NPC1 | |
| SCHEMBL3722514 | 0.77 | KMT2A (0.50) | MEN1KMT2ANPC1 | |
| SCHEMBL16700858 | 0.77 | KMT2A (0.48) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31326473 | 0.77 | MAPT (0.59) | HMOX1MAPTMEN1KMT2AFFAR1 | |
| Nitric Acid SCHEMBL16700597 | 0.76 | KMT2A (0.47) | MAPTMEN1KMT2ANPC1LMNA | |
| Trifluoroacetic Acid SCHEMBL16700179 | 0.75 | KMT2A (0.49) | MAPTMEN1KMT2ANPC1 | |
| SCHEMBL23222102 | 0.75 | KMT2A (0.64) | MAPTHRH3MEN1KMT2ANPC1 | |
| SCHEMBL6582303 | 0.75 | LTA4H (0.59) | HMOX1MAPTHRH3KMT2ALTA4H | |
| SCHEMBL13919517 | 0.74 | MAPT (0.65) | HMOX1MAPTMEN1KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022241-A2 | NOVEL HIGH AFFINITY QUINOLINE-BASED KINASE LIGANDS | SCHERING CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |